What is MIT OpenCourseWare? The following is a sample of the free course materials provided by MIT for your Self Directed Learning. Materials include pdf files and videos and much more.
MIT OpenCourseWare is a free publication of MIT course materials that reflects almost all the undergraduate and graduate subjects taught at MIT.
Prof. Eric Lander
Prof. Robert Weinberg
Dr. Claudette Gardel
Prof. Andrew Chess
This course features a complete set of video lectures by Professor Eric Lander, Director of the Broad Institute at MIT and a principal leader of the Human Genome Project and Professor Robert A. Weinberg, winner of the 1997 National Medal of Science.
Education development efforts for these introductory biology courses are one of many activities conducted by the HHMI Education Group at MIT. This group focuses on curriculum development work for creating teaching tools in undergraduate biology courses.
The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material.
7.012 focuses on the exploration of current research in cell biology, immunology, neurobiology, genomics, and molecular medicine.
Acknowledgements
The study materials, problem sets, and quiz materials used during Fall 2004 for 7.012 include contributions from past instructors, teaching assistants, and other members of the MIT Biology Department affiliated with course #7.012. Since the following works have evolved over a period of many years, no single source can be attributed.
Useful Biology resources available on the Internet, including:
MIT's OpenCourseWare (see specifically the 7.01x classes in the Biology section.)
Wikipedia on Biology (try links in the introduction such as Microb...
The Online Biology Book, hosted by Estrella Mountain Community Col...
Readings click here
Freeman, Scott. Biological Science. Upper Saddle River, NJ: Prentice Hall, 2002. ISBN: 9780130819239.
LEC # TOPICS READINGS click here
1 Introduction p. vi
Chapter 1
pp. 90-94
2 Biochemistry 1 Chapter 2
pp. 70-77
3-5 Biochemistry 2
Biochemistry 3
Biochemistry 4 Chapter 3
Chapter 6
6 Genetics 1 Chapter 10, pp. 194-201
7 Genetics 2 Chapter 10, pp. 201-214
8 Genetics 3 Chapter 8.2 (pp. 159-164) and pp. 176-191
9 Human Genetics Chapter 17.2, pp. 339-342
10 Molecular Biology 1 pp. 59-61, Chapter 11, 12
11 Molecular Biology 2 Chapter 13, pp. 252-259
Quiz 1, Lectures 1-10
12 Molecular Biology 3 Chapter 13, pp. 259-271, 244-246
13 Gene Regulation Chapter 14
14 Protein Localization Protein Trafficking. pp. 95-103
15-18 Recombinant DNA 1
Recombinant DNA 2
Recombinant DNA 3
Recombinant DNA 4 Spencer, Charlotte A. Genetic Testimony: A Guide to Forensic DNA Profiling. San Francisco, CA: Benjamin Cummings, 2003. ISBN: 9780131423381.
Quiz 2, Lectures 11-17
19 Cell Cycle/Signaling pp. 164-168, 864-867
20 Cancer Weinberg, R. A. "How Cancer Arises." Sci Am. 275, no. 3 (September 1996): 62-70.
———. "Finding the Anti-oncogene." Sci Am. 259, no. 3 (September 1998): 44-51.
21 Virology/Tumor Viruses Chapter 26, pp. 501-507
Viruses (PDF)
22-23 Immunology 1
Immunology 2 Chapter 46
Humoral Immunology (PDF)
24 AIDS Chapter 26.2, pp. 507-516
AIDS (PDF)
25 Genomics Lander, E. S., and R. A. Weinberg. "Genomics: Journey to the Center of Biology."Science 287, no. 5459 (March 10, 2000): 1777-82.
Quiz 3, Lectures 18-24
26 Nervous System 1 Chapter 42, pp. 806-817
27 Nervous System 2 Chapter 42, pp. 817-822
28 Nervous System 3 Chapter 42, pp. 822-827
29-30 Stem Cells/Cloning 1
Stem Cells/Cloning 2 pp. 346, 406-407, 364-367
Essay on p. 826
Growth and Differentiation, a Case of Hematopoiesis (PDF)
31 Molecular Medicine 1 NCI Gleevec Article
pp. 330
32 Molecular Evolution Genetics and Geneology, Why Y?
The Family Lemba (PBS Nova)
The Family Cohanim (PBS Nova)
Did Thomas Jefferson Father Slave Children? (PBS Nova)
33 Molecular Medicine 2 Essay: pp. 782-783
The Cholesterol Quartet
Familial Hypercholesterolemia
34 Human Polymorphisms and Cancer Classification
35 Future of Biology
Recitations click here
Recitation problems cover material discussed in the corresponding lecture sessions.
LEC # RECITATION PROBLEMS SOLUTIONS
1 Cell Section Problem (PDF)
Cell Section Answer (PDF)
3-5 ChemProb (PDF)
ProteinProb (PDF)
ChemProb Answers (PDF)
ProteinProb answers (PDF)
6 Genetics (PDF)
Genetics Answers (PDF)
7 Comp/Epi (PDF)
Comp/Epi Answers (PDF)
9 Pedigrees (PDF)
Pedigrees Answers (PDF)
10 Chart (PDF)
Mes/Stahl (PDF)
Replication (PDF)
Chart Answers (PDF)
Replication Answers (PDF)
12 Central Dogma (PDF)
Central Dogma Answers (PDF)
14 Gene Regulation (PDF)
Protein Secretion (PDF)
Gene Regulation Answers (PDF)
Protein Secretion Answers (PDF)
15-18 Rec. DNA (PDF)
Forensic Sect. (PDF)
Rec. DNA Answers (PDF)
Forensic Answers (PDF)
19 Cell Cycle (PDF)
Signal Transduction (PDF)
Cell Cycle Answers (PDF)
Signal Transduction Answers (PDF)
21 Cancer 1 (PDF)
Cancer 2 (PDF)
Cancer 3 (PDF)
Cancer 1 Answers (PDF)
Cancer 2 Answers (PDF)
Cancer 3 Answers (PDF)
22-23 Immunology 1 (PDF)
Immunology 1 Answers (PDF)
24 Immunology 2 (PDF)
Aids (PDF)
Jeremy's Quiz (PDF)
Immunology 2 Answers (PDF)
Aids Answers (PDF)
Jeremy's Quiz Answers (PDF)
26 Neuro I (PDF)
Neuro I Answers (PDF)
27 Neuro II (PDF)
Neuro II b (PDF)
Neuro II Answers (PDF)
Neuro II b Answers (PDF)
29 Stem Cells (PDF)
Stem Cells Answers (PDF)
31 Stem Cell Review/Cloning (PDF)
Stem Cells Review/Cloning Answers (PDF)
32 Evolution I (PDF)
Evolution II (PDF)
Evolution I Answers (PDF)
Evolution II Answers (PDF)
34 Rational Medicine (PDF)
Rational Medicine Answers (PDF)
Assignments click here
ASSIGNMENTS SOLUTIONS
Problem Set 1 (PDF)
(PDF)
Problem Set 2 (PDF)
(PDF)
Problem Set 3 (PDF)
(PDF)
Problem Set 4 (PDF)
(PDF)
Problem Set 5 (PDF)
(PDF)
Problem Set 6 (PDF)
(PDF)
Problem Set 7 (PDF)
(PDF)
Exams click here
PRACTICE EXAMS EXAM SOLUTIONS
Quiz 1 (PDF)
Quiz 1 (PDF)
Quiz 2 (PDF)
Quiz 2 (PDF)
Quiz 3 (PDF)
Quiz 3 (PDF)
The downloadable practice exams include solutions at the end of each respective file. Exams are provided as solutions files.
The Final Exam is a 3-hour, cumulative exam, covering the entirety of the course.
Practice final exam (PDF)
Study Materials click here
Fall 2003 Assignments
ASSIGNMENTS SOLUTIONS
Lecture Handouts
LEC # HANDOUTS
Video Lectures click here
LEC # TOPICS
1 Introduction
2 Biochemistry 1
3 Biochemistry 2
4 Biochemistry 3
5 Biochemistry 4
6 Genetics 1
7 Genetics 2
8 Genetics 3
9 Human Genetics
10 Molecular Biology 1
11 Molecular Biology 2
12 Molecular Biology 3
13 Gene Regulation
14 Protein Localization
15 Recombinant DNA 1
16 Recombinant DNA 2
17 Recombinant DNA 3
18 Recombinant DNA 4
19 Cell Cycle/Signaling
20 Cancer
21 Virology/Tumor Viruses
22 Immunology 1
23 Immunology 2
24 AIDS
25 Genomics
26 Nervous System 1
27 Nervous System 2
28 Nervous System 3
29 Stem Cells/Cloning 1
30 Stem Cells/Cloning 2
31 Molecular Medicine 1
32 Molecular Evolution
33 Molecular Medicine 2
34 Human Polymorphisms and Cancer Classification
35 Future of Biology
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